Researchers at New York University (NYU), Columbia University, and the New York Genome Center have developed an artificial intelligence (AI) platform that can predict on- and off-target activity of ...
Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology. The study by researchers at ...
In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short ...
In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...
The study combines a deep learning model with CRISPR screens to control the expression of human genes in different ways -- such as flicking a light switch to shut them off completely or by using a ...
Using a CRISPR-based genetic screen, Cellecta recently identified, for a client, a class of proteins responsible for regulating gene expression of a genetic element present in the 5′-untranslated ...
CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...
Bacteria-attacking viruses, known as bacteriophages, use small RNAs to disarm the CRISPR-Cas immune systems of bacteria. This discovery has now been documented by researchers at the University of ...
A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...
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