Ribonucleic acids (RNAs) are single-stranded molecules that play an essential role in the cells of all living organisms. As "transcripts" of our genes, mRNAs, for example, are involved in the ...

Scientists at the University of Birmingham and the Francis Crick Institute have discovered a new way in which cancer cells repair double-stranded breaks in DNA. The findings were published in a paper ...

Researchers are actively searching for ways to extend the survival benefit of targeted cancer therapies to prevent the possibility of highly resistant tumors. A new study led by researchers at the ...

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes - critically important ...

Complex biological processes like aging require a broad investigation of multiple mechanisms (Cohen et al., 2022). Computational modeling has been proven successful in studying specific pathways, but ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence emerging as a key driver in its pathogenesis. This overview synthesizes ...

Prime editing is an improved variant of the CRISPR/Cas system that can introduce alterations in DNA with exquisite precision. But the method is complex and inefficient. A research group has now been ...

That inevitability of growing older might not be as fixed as we once believed. Emerging research has begun challenging our most fundamental assumptions about aging, revealing that cellular ...

Gene editing technologies, such as CRISPR, can cause unintended alterations in the genome which may be potentially dangerous. A multidisciplinary team of scientists led by Britt Adamson at Princeton ...