Liquid culture flasks of bacteria grown in yellow broth covered with tinfoil on a shaker. Bacterial strains needed to be tested every step of the way to create the highly compressed genome. Credit: ...
The code of life is simple. Four genetic letters arranged in triplets—called codons—encode amino acids. These are the building blocks of proteins, the machinery that powers life. But the genetic code ...
AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining ...
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