Halogen bonds were first proposed as an activating interaction in 2008, but this alternative type of organocatalysis was ...

A research team from Hokkaido University has confirmed a century-old theory by discovering a stable single-electron covalent bond, known as a sigma bond, between two carbon atoms. This unique bond ...

The loss of insulin-producing beta cells is a root biological cause of type 2 diabetes and its progression. BMF-219, a novel covalent menin inhibitor, is designed to potentially regenerate, preserve, ...

<Figure 1. Schematic of the diffusion model developed by the research team, which generates molecular structures and non-covalent interactions based on protein structures. Starting from a noise ...