Objectives The aim of the study was to ascertain frequency of clinical manifestations in patients with CREST variant related to skin involvement in SSc. Methods Since 1993 we have treated 184 patients ...

Dear Dr. Roach: I am a 76-year-old woman in good health, although I am overweight. I was recently diagnosed with CREST syndrome. I’m finding it difficult to learn more about this autoimmune disease.

CREST syndrome, or limited systemic sclerosis, is a rare autoimmune disease that causes changes and scarring of the body's blood vessels and connective tissues. The acronym CREST stands for the main ...

We describe a patient with scleroderma (CREST syndrome) and central nervous system vasculitis. While angiography demonstrated segmental symmetrical arterial narrowing characteristic of vasculitis, ...

Background Systemic sclerosis (SSc) is a connective tissue disease characterized by excessive collagen deposition and by vascular hyperactivity and obliteration of microvasculopathy. Raynaud ...

Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs. Systemic sclerosis (SS) is an autoimmune ...