Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Exactly 66 years ago, on April 25, 1953, Francis Crick and James Watson published their famous article that showed that the shape of DNA is a double helix. They weren’t able to see DNA directly - it’s ...

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear, isolating communities from vital resources.

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

The DNA crystals could potentially be used as the basis of a programmable material platform. Development of these intricate structures could lead to new advances in computing, biology and many other ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...