DPP-4 exists as both a membrane-bound and soluble form. DPP-4 has historically been associated with its capacity to metabolize incretin hormones. Recent studies have identified additional functions of ...
Introduction: Diabetes Mellitus (DM) constitutes a global epidemic and is one of the top ten leading causes of mortality (WHO, 2019), projected to rank seventh by 2030. The US National Diabetes ...
Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan Aim: At present, daily DPP-4 inhibitors are quite frequently prescribed in subjects with type 2 diabetes ...
CXCR3 is a chemokine receptor with three ligands: CXCL9, CXCL10, and CXCL11. Cancer patients with low CXCL9 or CXCL10 levels exhibit a reduced response to the main immune checkpoint inhibitor PD-1, as ...