RNA editing covalently alter the nucleotide sequence of RNA transcripts relative to that of the encoding DNA, thereby contributing to gene diversity 1. One of the most prevalent RNA modifications is ...
Figure 1: EndoV 3′ incision initiating deaminated adenine repair. To characterize DNA-repair initiation for this prototypic enzyme, we solved the crystal structures of T. maritima EndoV in complex ...
Researchers have determined the detailed three-dimensional structure of part of the flu virus' RNA polymerase, an enzyme that is crucial for influenza virus replication. The research was done on the ...
Emerging influenza viruses are a serious threat to human health because of their pandemic potential. A promising target for the development of novel anti-influenza therapeutics is the PA protein, ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 10 (Oct., 1979), pp. 4778-4782 (5 pages) Among the mediators of interferon action are one enzyme that is ...
Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...
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