David Baker's lab at the University of Washington is announcing two major leaps in the field of AI-powered protein design.
A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic ...
Nobel laureate David Baker’s latest foundation model can design proteins that interact to any biomolecule for broad biotech applications.
Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model ...
Structural models of PLD3 and PLD4, enzymes that degrade nucleic acids in the cytoplasm. The enzymes' active (or binding) sites are indicated with black arrows. LA JOLLA, CA—When nucleic acids like ...
Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of ...
Cell death triggered by GPX4 loss was slowed in cell cultures and in mouse model using compounds that specifically inhibit ferroptosis.
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and ...
Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning. The models also can show how genetic mutations alter the enzymes' behavior in ways that ...
Your gut microbes play a major role in how well you absorb nutrients, explaining why identical diets produce very different results.