Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of sperm ...

Humans have 23 pairs of chromosomes, including a pair of sex chromosomes (typically XX for females, and XY for males). Chromosomes contain hundreds to thousands of genes, which are sections of DNA ...

The male-determining sex chromosome has lost 97 percent of its ancestral genes in the last 300 million years. If that rate ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't ...

Female mammals have a higher risk of developing autoimmune conditions such as lupus because extra copies of genes that are supposed to be permanently turned off get reactivated as they grow older, a ...

KIT researchers succeeded for the first time in reducing the number of chromosomes in a plant using the CRISPR/Cas method – surprisingly without affecting its growth The CRISPR/Cas molecular scissors ...

The lab of developmental biologist Dr. Eric Lai has been studying evolutionary battles of the sexes in fruit flies. This colorful snapshot, courtesy of the Lai Lab, depicts sperm maturation in fruit ...

This is a preview. Log in through your library . Abstract Haplodiploidy and paternal genome elimination (HD/PGE) are common in invertebrates, having evolved at least two dozen times, all from male ...

The silencing of the one X chromosome in XX cells is mediated by XIST, a long noncoding RNA that is randomly transcribed from only one X early in development. It coats the DNA and shuts down gene ...

Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and females. A study led by bioengineers at the University of ...