The human Y chromosome, responsible for male sex determination, has forfeited 97% of its ancestral genes over the past 300 ...

Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of sperm ...

Humans have 23 pairs of chromosomes, including a pair of sex chromosomes (typically XX for females, and XY for males). Chromosomes contain hundreds to thousands of genes, which are sections of DNA ...

Female mammals have a higher risk of developing autoimmune conditions such as lupus because extra copies of genes that are supposed to be permanently turned off get reactivated as they grow older, a ...

The lab of developmental biologist Dr. Eric Lai has been studying evolutionary battles of the sexes in fruit flies. This colorful snapshot, courtesy of the Lai Lab, depicts sperm maturation in fruit ...

Bacterial chromosome dynamics and gene regulation are intimately linked through a finely orchestrated interplay between the physical organization of the chromosome and the molecular processes that ...

KIT researchers succeeded for the first time in reducing the number of chromosomes in a plant using the CRISPR/Cas method – surprisingly without affecting its growth The CRISPR/Cas molecular scissors ...

The silencing of the one X chromosome in XX cells is mediated by XIST, a long noncoding RNA that is randomly transcribed from only one X early in development. It coats the DNA and shuts down gene ...

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't ...