New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a ...

How do cells know what they should become as the body develops? Biological development depends crucially on spatial patterns: the lines that eventually give rise to segments, organs, or markings like ...

MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

Your DNA is constantly changing. And if it weren’t for genetic mutations, evolution wouldn’t exist. So, what would life be like if that stopped? What causes your DNA to change? How would your life ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe. Using advanced analysis based ...

An ancient ancestor of spiders and relatives doubled its genome about 400 million years ago, setting the stage for the ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed ...

Tobacco smoking is linked to specific genetic mutations in MDS, affecting chromatin modification and RNA splicing pathways. A dose-response relationship exists, with higher smoking intensity ...