The quest for a vaccine against HIV has been going on for about 40 years — almost as long as the virus that causes AIDS has been known to scientists and the public. There has been some progress ...
In his new book, “The Catalyst,” Dr. Thomas Cech describes how mRNA in the COVID vaccines encodes the virus’s spike protein. The following is an excerpt from The Catalyst: RNA and the Quest to Unlock ...
Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.
A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the destruction of disease-causing mRNA. Achieving the opposite and stabilizing health-promoting mRNA is still ...
Scientists from CNRS have developed new stable and effective messenger RNA (mRNA) sequences that enable cells to produce therapeutic proteins themselves, capable of inducing antibody production ...
The metaphors we used to describe DNA make it sound almost sacred. Proteins, too, are revered. They are the “workhorses of the cell.” They make things happen. RNA, by contrast, has not been so exalted ...
Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...
The central dogma of molecular biology showing what is happening in this study. Credit: Julian Chen For the very first time, a study led by Julian Chen and his group in Arizona State University's ...
Philadelphia, August 15, 2025 – A new study, led by researchers at Children’s Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma ...
mRNA transports the most valuable cellular information - the chemical blueprint for the production of proteins - from the nucleus into the cytoplasm. However, as soon as mRNA has delivered its message ...