Interferons are a basic way that our bodies fight everything from the sniffles to certain cancers. Released by cells when threatened, these proteins tell nearby cells to, in a sense, “interfere” with ...

Impaired termination of immune responses is detrimental and often results in chronic inflammation and disease. Most activated T cells and B cells die after antigen clearance, and only a small fraction ...

In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...

Antiviral therapy without interferon improved liver function in patients with hepatitis C virus infection-related advanced cirrhosis, according to data from an observational cohort study. Researchers ...