Genomic technologies have revolutionized our understanding of complex Mendelian diseases and cancer. Solid tumors present several challenges for genomic analyses, such as tumor heterogeneity and tumor ...

To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium chloride/ethidium bromide (CsCl/EtBr) gradient ...

Analysis of short tandem repeats (STR) by PCR analysis is routinely used in chimerism diagnostics to monitor donor engraftment and to diagnose relapse. Some applications require chimerism analysis of ...

Requirements placed on samples to be processed continue to grow. In both academic settings and industry, automation solutions are becoming more and more important. The purification of genomic DNA ...

Learn how genomes from 28 ancient individuals show that Homo sapiens lived in southern Africa in near isolation for hundreds ...

Take a look behind the scenes of a recent Reports article, entitled: ‘Rapid extraction of DNA suitable for NGS workflows from bacterial cultures using the PDQeX’, as we ask authors about PDQeX, a new ...

Many of the ancient southern Africans, including those who lived between about 10,200 and 1,400 years ago, "fall outside the ...

Researchers have developed a new method to prepare bone powder for ancient DNA extraction. The method outperformed previous techniques of decontaminating ancient bones. Researchers from Max Planck ...

PLEASANTON, Calif.--(BUSINESS WIRE)--Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, No. 14, [Part 1: Biological Sciences] (Jul. 15, 1982), pp. 4437-4441 (5 pages) The DNA genome of a human ...

New research reveals ancient humans in southern Africa lived in isolation for nearly 100,000 years. This led to unique ...

I have spent years covering discoveries that nudge our origin story around the edges, but the sequencing of DNA from one of the very last Neanderthals does something different: it rewrites the center ...