Mitogen-Activated Protein Kinase (MAPK) signalling pathways represent a fundamental means by which cells translate extracellular stimuli into a wide array of intracellular responses, including ...

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers have investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to ...

Researchers are combining a range of techniques for analyzing key cell signaling pathways in drug discovery and therapeutic development, according to presentations at Cambridge Healthtech’s “Molecular ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...

Raf kinases are components of the MAP kinase pathway, a signal transduc-tion pathway that normally controls cell growth and division downstream of activated cell surface growth factor receptors. RAF1, ...

Plants, insects and mammals have a conserved innate immune system that is the first inducible defense against infectious disease, but the exact nature of the signaling molecules in this system remains ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...