The ability of microarrays to measure thousands of RNA transcripts at one time allows for the characterization of cells and tissues in greater depth than was previously possible, but has not yet led ...

Jonathan Weissman at the University of California, San Francisco wants to know how cells fold proteins into the right shapes, and he knocks down genes to find out. For that he uses massive RNA ...

RNA interference technology, which is used in cell biology, has revolutionized functional research of the gene products in the last ten years. Now researchers have developed a method which allows a ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

Interim Executive Director, Biodesign Institute Director, Biodesign Institute's Virginia G. Piper Center for Personalized Diagnostics; Virginia G. Piper Chair of Personalized Medicine; Pr ...

In order to keep pace with rapid advancements in protein microarray technology, detection systems have also been significantly improved. Important parameters critical for the success of various ...

A protein microarray consists of the immobilization of proteins in organized rows and columns upon a support structure. The structure of the protein microarray allows for high-throughput analysis of ...

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

Curious about how to detect and characterize tumor-derived biomarkers from liquid biopsy samples? Genomics-based methods now provide access to more molecular data than ever before, delivering cancer ...

Many recently developed pneumococcal serotyping methods detect the dominant serotype in a laboratory or field sample, but several fail to detect minor serotypes, according to a study published this ...

Abbreviations: Fig, figure; UA, unavailable; FFPE, formalin-fixed, paraffin-embedded. Histological types include squamous cell carcinoma, adenocarcinoma, and large cell carcinoma in pre-validation ...