Figure 1: Synthetic strategies to access secondary and tertiary alcohols by carbonyl addition reactions. Despite considerable advances, and the abundance of organometallic reagents developed for ...

Understanding the delicate balance between nucleophilicity and electrophilicity is fundamental to rationalising reaction mechanisms in organic chemistry. Nucleophilic reactivity describes a molecule’s ...

The metalloenamines, generated via the NH-deprotonation of β,β-disubstituted enesulfinamides using lithium diisopropylamide (LDA), participate in stereoselective nucleophilic addition reactions with β ...

College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou 311121, P. R.

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...