The latest short science news items from C&EN. Watanabe and coworkers tested the probe with colon cancer tissue samples in 96-well plates. The probe revealed the presence of colibactin-producing ...

Detecting problems with lysosomes is the focus of a new set of fluorescent probes. "A lot of diseases are related to problems with lysosome functions," says a chemistry doctoral candidate involved in ...

Fluorescent probes have emerged as indispensable tools in the detection of carbon monoxide (CO) within living systems, owing to their high sensitivity, selectivity and rapid response times. CO, ...

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is ...

This is not just another tool to image cancer. The probe is a two-for-one: detect cancer and distinguish one type from another. Together, they develop a cancer fingerprint. Determining the presence of ...

NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development. Since its ...

A fluorescent probe developed by Michigan Tech chemist Haiying Liu illuminates the enzyme beta-galactosidase in a cell culture, which could help cancer surgeons. What if you could plaster cancer cells ...

Researchers at Cornell University are working on improving the trial-and-error process that is implicated in finding effective molecules for drug delivery ...

Subtle cognitive decline in early Alzheimer’s disease is often indistinguishable from normal aging; as a result, the disease readily goes undiagnosed for two to three years after symptom onset. By ...

Probes used in life-cell fluorescence imaging must be able to penetrate cells and bind specifically to the protein of interest. Ideally, such probes also increase their fluorescence intensity when ...