Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute lymphoblastic leukemia (T-ALL), differently depending on genetic ancestry. The ...

Your body contains trillions of cells, each carrying out specific functions to keep you alive. According to a 2016 article in PLOS Biology, about 97% of these cells are made up of red blood cells, ...

Scientists at Duke-NUS Medical School and the National University Health System (NUHS), together with an international team ...

The root causes of most forms of Alzheimer’s disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle. Unexpectedly, the investigators found that 45 of 80 autopsy ...

Is Obesity Genetic or Environmental? Get All the Details This article was reviewed by Lynn Marie Morski, MD, JD. Key ...

Researchers have discovered a rare new type of diabetes that affects babies early in life. The condition is caused by changes ...