A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Scientists have pinpointed precise regions in the human genome where DNA is most likely to develop a mutation.

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

BKPyV infection is often asymptomatic or mild during childhood, but may leave a lasting impact on cancer risk. In A Nutshell ...

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...