A new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond ...
A cutting-edge base-edited CAR T-cell therapy is opening a revolutionary new frontier for patients battling aggressive T-cell leukemia.
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.
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CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study
A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...
After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...
Researchers have discovered that tiny cell structures called primary cilia help repair DNA in bile duct cells, opening new possibilities for treating bile duct and other cancers with limited options.
Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...
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New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
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