In all forms of gene therapy, DNA exerts its influence from within the nucleus. Recombinant events for viral delivery of plasmid DNA are permanent and alter the genomes of the affected cells and their ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level – the chemical tags in DNA that help regulate gene expression – between two ...

In a world first, researchers have identified a new DNA structure -- called the i-motif -- inside cells. A twisted 'knot' of DNA, the i-motif has never before been directly seen inside living cells.

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Scientists continue to inch closer and closer to medical breakthroughs by tinkering with DNA. At the end of 2016, the CRISPR gene-editing tool was used for the first time on human cancer patients, and ...

Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

Using DNA, the blueprint of life, U.S. researchers said they have made a three-dimensional structure from particles of gold in a development that could lead to a host of custom-designed materials. The ...

It's DNA, but not as we know it. In a world first, Australian researchers have identified a new DNA structure - called the i-motif - inside cells. A twisted 'knot' of DNA, the i-motif has never before ...