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Scientists Say This Weight-Loss Drug Is Like ‘Exercise in a Pill’—But What Do Doctors Think?
An experimental new medication claims to help people lose weight without muscle loss. Here’s what you need to know about the ...
The FDA is weighing the regulatory fate of KarXT — an oral dual M1/M4 muscarinic acetylcholine receptor (mAChR) agonist — for schizophrenia. If approved, the fixed-dose combination of xanomeline and ...
New psychoactive substances, originally developed as potential analgesics but abandoned due to adverse side effects, may ...
The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the ...
This new technique for studying cell receptors could have sweeping implications for drug development
Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...
A preliminary study of people with diabetes suggests that use of glucose-lowering GLP-1 drugs may be linked to a lower risk ...
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...
Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells. Researchers show that engaging serotonin 2A ...
Humans have bitter taste receptors not only in their mouths but in their lungs, too. Researchers have exploited these receptors’ innate ability to dilate the airways to create a potent new drug that ...
Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors ...
Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells. In a paper published Feb. 17 in Science, ...
A cortical neuron (white) with colored dots showing the locations of serotonin 2A (5-HT2A) receptors. New work shows that these receptors produce different effects when they are inside or on the ...
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