During the last 50 years, an abundance of data has been gathered on the function of lipids as a source of energy, as building blocks, and as signaling molecules in living systems. Lipid-signaling ...

Biochemical assays are a common approach used to identify inhibitors of epigenetic-modifying enzymes. Challenges that arise when designing these assays are centered on choosing histone substrates that ...

The Metabolic Disease Laboratory provides services for the diagnosis of lysosomal storage diseases. The laboratory provides screening of urine for glycosaminoglycans, oligosaccharides, sialic acid, ...

A new type of assay based on click chemistry will make it possible to carry out high-throughput screens to find inhibitors of the gut hormone ghrelin, a target for obesity and diabetes medications.

The application of detailed mechanistic enzyme kinetics is vital for the characterization of enzyme targets; furthermore, it is crucial to aid in the design and prosecution of assays to effectively ...

AMSBIO (Oxford, UK) has launched a new range of deubiquitinating (DUB) enzyme assay kits supplied in a convenient and easy-to-use 96-well assay format. With minimal setup required and no need for ...

If your doctor suspects you have one of several diseases, they may want to perform an “enzyme-linked immunosorbent assay” test. This is more commonly known as an ELISA test, and it can help to confirm ...

RNA helicases are a group of enzymes that bind to and alter RNA in an ATP-dependent way. They play significant roles in RNA metabolism, gene expression regulation, and innate immunity. Different RNA ...

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death. Cancer cells that are resistant to anticancer drugs are known to be ...