Scientists from the Université de Montréal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to ...

Researchers from CIIMAR and the University of Helsinki have discovered a new biochemical modification in natural ...

We have synthesized a hybrid subtilisin the solubility of which can be regulated by photoirradiation through coupling with a photoresponsive copolymer that carries spiropyran groups in its side chains ...

A consortium of scientists has discovered new non-histone targets for one enzyme previously believed to modify only histones -- the group of proteins that creates tightly bundled packages of DNA ...

A seemingly subtle swap of metals—substituting a zinc ion with a cobalt ion—and a mutation ramps up the overall electric field strength at the active site of an enzyme, Stanford scientists find. The ...

One of these days, the ability of our cells and tissues to regenerate and repair themselves will come to a stop. Researchers hoping to better understand the processes that regulate aging are studying ...

Covalent attachment of ubiquitin and SUMO to proteins plays a major role in regulating cellular functions. Both modifications depend on a similar enzymatic cascade. Ubiquitination involves a single E1 ...

The enzyme ALKBH1 can remove molecular modifications from transfer RNA, causing a measurable effect on protein translation in the cell, new research demonstrates. The study sheds new light on how ...

Cellular RNAs are chemically modified by many RNA modification enzymes; however, often the functions of modifications remain unclear, such as for pseudouridine formation in the tRNA TΨC arm by the ...