Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Endosomal and cytosolic nucleic acid receptors sense microbial nucleic acids and initiate innate immune responses. However, in some circumstances their activation by endogenous nucleic acids can also ...

Nucleic acids are chains of nucleotides that are a vital part of all living beings. The two most common types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which provide ...

Our research teams focus on all aspects of nucleic acids in health and disease, with the goal of better understanding basic processes and developing therapeutic interventions to improve human health.

The purpose of the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (known as the NIH Guidelines (PDF) is to specify the practices for constructing and handling: ...

Some biologists have long hoped that small pieces of RNA that silence genes could help wipe out genetic diseases. But developing nucleic acid medications with good drug properties, such as selectivity ...

The market potential of nucleic acid-based therapies have been pushed into the spotlight following the success of the COVID-19 vaccines. According to Carl Schoellhammer, PhD, principal at DeciBio ...