An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

For decades, Arieh Warshel, USC Distinguished Professor of Chemistry and a 2013 Nobel laureate, has used computer simulations ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...

A large hospital-based cross-sectional study examined whether routinely measured serum alkaline phosphatase can indicate ...

Cell death triggered by GPX4 loss was slowed in cell cultures and in mouse model using compounds that specifically inhibit ferroptosis.

An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...

The inaugural competition surprisingly awarded two $100,000 grand prizes to address challenges in defining robust benchmarks for complex biology.

Scientists have developed a new method to boost the energy of aging or damaged cells, an innovation that could improve ...

A microorganism has been discovered that breaks biology’s golden rule. This genetic twist could change everything.

Your gut microbes play a major role in how well you absorb nutrients, explaining why identical diets produce very different results.

Researchers have uncovered a mechanism that protects nerve cells from premature cell death, providing the first molecular ...