Leading synthetic biologists have shared hard-won lessons from their decade-long quest to build the world's first synthetic ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

“Tracker” ended its second season as the No. 1 scripted show on television this past spring, which means the upcoming Season 3 premiere could not be more highly anticipated. Luckily for fans of the ...

CRISPR powers everything from gene editing to rapid diagnostics, but how did one of its most versatile branches arise? A new Cell study, “Functional RNA splitting drove the evolutionary emergence of ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

In biology’s standard tale of two acids — deoxyribonucleic (DNA) and ribonucleic (RNA) — RNA is merely the messenger. Its better-known cousin DNA plays the lead role, issuing genetic instructions for ...

This paper describes RNA-sensing guide RNAs for controlled activation of CRISPR modification. This works by having an extended guide RNA with a sequence that folds back onto the targeting sequence ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Department of Botany, Faculty of Science, Dayalbagh Educational Institute, Agra, Uttar Pradesh, India Recent breakthroughs in CRISPR/Cas genome editing have transformed molecular biology research and ...

“The Federal Circuit clarified that for anticipation under § 102, enablement requires only one operable embodiment, not the full scope of claims mandated under § 112.” In a precedential decision ...