Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been ...

AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...

In a report published in the Proceedings of the National Academy of Sciences, researchers working at Florida State University (FSU), Baylor College of Medicine and the Broad Institute of Harvard and ...

Molecular biologists long thought that domains in the genome's 3D organisation control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, EMBL researchers now reveal ...

Human chromosomes behave in much the same way as those of rodents, primates, and other close evolutionary cousins. But researchers don’t know whether those similarities might extend to distantly ...

Click to share on X (Opens in new window) X Click to share on Facebook (Opens in new window) Facebook For many years, scientists thought they understood the inactivity of X chromosomes in females.

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy ...

Research showed that a regulatory protein of chromosome structure (cohesin) is essential for proper maintenance of gene expression in the developing brain. Reduced cohesin impaired development of ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...