Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

ASH 2025 research shows cancer can arise not just from mutations but from broken DNA architecture. AI reveals how lost genome loops silence tumor suppressor genes.

While prokaryotic cells do not have membrane-bound structures, they do have distinct cellular regions (Figure 1). In prokaryotic cells, DNA bundles together in a region called the nucleoid. Primitive ...

Research shows synthetic chromosomes can be transferred to human cells with potential to improve viral resistance ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...