A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

The first 100 bases of many genes show excess mutations, revealing a major genomic weak spot that shapes disease risk and ...

"Adapt or perish, now as ever, is nature's inexorable imperative," wrote H. G. Wells. This principle—that survival requires ...

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of ...

We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...