First human DNA-cutting enzyme that senses physical tension discovered

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...
eLife

The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States ...
Medical Device and Diagnostic Industry (MD+DI)

Next-Gen Sequencing Is Going Global, And 2026 Could Be the Tipping Point

Revvity targets 2026 growth with multiomics, AI-powered base editing, NGS newborn screening, and immunotherapy advances.
eLife

Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation

This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...
Scientific Research Publishing

Urine-Based Liquid Biopsy for Detecting Recurrence of Bladder Cancer ()

Xu, W. , Xing, X. and Cheng, S. (2025) Urine-Based Liquid Biopsy for Detecting Recurrence of Bladder Cancer. International ...