Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

DNA scaffolds that mirror influenza virus protein geometry boost antiviral binding and reduce infection more effectively than free molecules, enabling a modular antiviral design strategy.

PhD Defense: From genes to enhancers and everything in between The role of enhancer distance in transcriptional regulation Anna-Karina Felder From genes to enhancers and everything in between: The ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...

He chronicled the search for ‘the secret of life’ in his bestseller The Double Helix but damaged his career with his controversial views ...