This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

One of the most important milestones in modern science, does April 25 also mark the date of an intellectual heist? As has been well-documented, a third person contributed to the discovery — the ...

As one of the inventors of next-generation DNA sequencing, Sir Shankar Balasubramanian could claim to be responsible for a revolution in the life sciences. Balasubramanian and chemist David Klenerman, ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...