CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study

A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
Science Daily

Scientists capture most detailed look inside DNA droplets

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...
Daily Excelsior

James Dewey Watson From DNA Double Helix to a Contested Legacy

Jyoti Vakhlu [email protected] From laws of inheritance to the molecule of heredity – a journey of scientific ...
eLife

Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

From the volcanic crater to the lab: Extremophiles offer a lesson in survival

"Adapt or perish, now as ever, is nature's inexorable imperative," wrote H. G. Wells. This principle—that survival requires ...
AZoLifeSciences on MSN

DNA Rigidity Inside the Nucleosome Regulates INO80 Positioning

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...
Technology Networks

DNA Shape, Not Just Sequence, Guides Gene Access

Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling ...

Under the Radar: How to Build a Private Equity Portfolio Using Public Stocks

Every few years the financial world rediscovers private equity and declares it the secret club where all the real money is ...

DNA shape and rigidity regulate key players of gene expression

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...