Gene therapy could be a permanent cure for many life-threatening hereditary diseases, and this will only help in the treatment of genetic diseases and cancer ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Whether you turn red when drinking alcohol, dislike certain smells, or metabolize drugs differently from others, the ...

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...

An international research team at the University of Hong Kong has discovered a human protein known as ANKLE1, which is ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), a spectrum of liver conditions ranging from simple ...

Northwestern University researchers are actively overturning the conventional view of iron oxides as mere phosphorus "sinks." A critical nutrient for life, most phosphorus in the soil is organic—from ...

For decades, Arieh Warshel, USC Distinguished Professor of Chemistry and a 2013 Nobel laureate, has used computer simulations ...

Saol Therapeutics received a complete response letter for its pyruvate dehydrogenase complex deficiency treatment a week ...

Researchers have given the gene therapy made at UManchester to two out of five planned patients in a Phase I/II trial, and ...

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...

The SARS-CoV-2 virus also depends on an enzyme, called M pro, to replicate in host cells. Because cruzain and M pro are ...