Researchers at the University of Toronto have harnessed a bacterial immune defence system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the ...

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

At the heart of molecular biology is the study of genetic material – DNA and RNA – which serve as the fundamental blueprints for life. These nucleic acids are not only essential for understanding how ...

This year marks the 25th anniversary of the publication of the Human Genome Project, a monumental scientific achievement that has transformed healthcare and laid the foundation for modern genomics.

We propose to generate high-density whole genome maps in nano-channels by combining Cas9- guide-RNA (gRNA) sequence-specific DNA labeling and motif-based DNA labeling. Cas9-guide- RNA (gRNA) DNA ...

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, ...