When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
The first 100 bases of many genes show excess mutations, revealing a major genomic weak spot that shapes disease risk and ...
With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...
The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...
After a spinal cord injury, cells in the brain and spinal cord change to cope with stress and repair tissue. A new study from Karolinska Institutet, published in Nature Neuroscience, shows that this ...
Tuberculosis (TB) is one of the oldest and deadliest infectious diseases we know. It commonly impacts the lungs, but can also affect other areas of the body like the spine, brain or kidneys.
Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling ...
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are linked to genes ...
Popular genetics tests can’t tell you much about your dog’s personality, according to a recent study. A team of geneticists ...