An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

For decades, Arieh Warshel, USC Distinguished Professor of Chemistry and a 2013 Nobel laureate, has used computer simulations ...

Two years after this, Sakaguchi was able to link these discoveries. He proved that the Foxp3 gene governs the development of ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic ...

Cell death triggered by GPX4 loss was slowed in cell cultures and in mouse model using compounds that specifically inhibit ferroptosis.

The SARS-CoV-2 virus also depends on an enzyme, called Mpro, to replicate in host cells. Because cruzain and Mpro are ...

Researchers have uncovered a mechanism that protects nerve cells from premature cell death, providing the first molecular ...

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ...

To understand how CBD may reduce pain, it’s important to learn the basics of the endocannabinoid system (ECS), a complex ...