CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study
A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...
A Nobel laureate, he identified an enzyme that cuts DNA, laying the groundwork for milestones in scientific research and ...
The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.
A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.
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Study uncovers principles guiding replication initiation across the human genome
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
The new recipients of the University’s fellowship scheme will receive support to develop independent research.
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
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