Analysing the gene activity of every single bacterial cell in a colony? A new technique of single-cell transcriptomics developed in W rzburg can do this much more efficiently than other methods: It ...

Bacteria aren’t just mindless microbes. Research by scientists at the Hebrew University of Jerusalem has revealed that single bacterial cells can carry a “memory” of their past environments—passing it ...

Antibiotic-driven modifications to ribosomal RNA (rRNA) have been suspected of giving rise to antibiotic resistance. For example, antibiotics can alter methylation patterns in rRNA, changing rRNA ...

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...

Microcolonies as a window into memory The Microcolony-seq method works by isolating tiny colonies that sprout from individual bacteria, analyzing their RNA, genomes, and physical traits. This approach ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Hyperthermophilic archaea are true survival experts. They thrive in boiling hot springs and deep-sea vents—environments ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

The cartoon illustrates how single-cell transcriptomics works: all mRNA molecules are recorded and characterized from countless bacterial cells, which are shown here in survival size on a conveyor ...

Bacteria aren’t just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a “memory” of their past environments—passing it down through ...