A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells ...

A new study has illuminated an important process that occurs during cell division and is a likely source of DNA damage under some circumstances, including cancer. A new study from scientists at the ...

Scientists from the Hebrew University have identified the molecular basis for DNA breakage, a hallmark of cancer cells. The findings of this research have just been published in the journal Molecular ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.