Researchers uncover a crucial hidden function of the protein RPA, revealing how its failure to activate telomerase leads to ...

Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to ...

A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of ...

A Nobel laureate, he identified an enzyme that cuts DNA, laying the groundwork for milestones in scientific research and ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...