Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Ultraprecise fluorescence nanoscopy techniques such as MINFLUX and RASTMIN are enabling molecular-scale imaging and tracking in biologically relevant conditions. However, their implementation is ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Scientists capture the most detailed 3D images of chromatin condensates, revealing how DNA packs tightly inside cells.

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...