Cancer isn't just about broken genes-it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services.

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the 'dark genome' that are responsible ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

Amyotrophic lateral sclerosis (ALS) affects nerve cells in the brain and spinal cord. The authors' approach to use genetic code expansion to tag two ALS proteins associated with stress granules has ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

A research team led by Prof. Sun Chaomin from the Institute of Oceanology of the Chinese Academy of Sciences (IOCAS) has ...

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

Researchers found that DNA's shape matters. When its loops break, cancer can start.Based on a new concept of architectural tumor ...