An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...
Vagus nerve-mediated neuroimmune modulation by electrical stimulation using an implantable device was well-tolerated and had durable efficacy through 12-months in adults with rheumatoid arthritis, ...
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