When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

Scientists have pinpointed precise regions in the human genome where DNA is most likely to develop a mutation. At spots where RNA polymerase 'opens' your DNA to read and copy instructions – known as ...