After running for one touchdown and 15 yards in his previous game (on two carries), Patrick Mahomes and the Kansas City Chiefs will play the Tennessee Titans in Week 16, on Sunday at 1 p.m. ET. Game Time: 1 p.m.

NASHVILLE, Tenn. (WSMV) - When the Tennessee Titans face the Kansas City Chiefs on December 21st, Patrick Mahomes will not be on the field.

The Chiefs-Titans game will be on CBS (KCTV 5 in Kansas City). In Wichita, it’s on KWCH (Channel 12). The game will also be broadcast on radio via KFNZ (96.5 FM) in the KC area and KNSS (98.7 FM) in the Wichita area. Despite losing Mahomes, the Chiefs are a 3 1/2-point favorite with the over/under set at 37 1/2.

The Tennessee Titans open as slight underdogs against the Kansas City Chiefs without Patrick Mahomes in Week 16.

Cam Ward threw a 34-yard TD to Gunnar Helm that trimmed the Tennessee Titans deficit to 14-10 against the San Francisco 49ers.

A skirmish breaks out in between Kansas City Chiefs and Los Angeles Chargers players after a helmet-to-helmet hit on Kansas City Chiefs wide receiver Tyquan Thornton (80) from Los