thorax.bmj

Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea

Background Non-invasive ventilation (NIV) is an effective form of treatment in patients with obesity hypoventilation syndrome (OHS) who have concomitant severe obstructive sleep apnoea (OSA). However, ...
thorax.bmj

Frequency and severity of respiratory infections prior to COPD diagnosis and risk of subsequent postdiagnosis COPD exacerbations and mortality: EXACOS-UK health care data study

Objective Little is known about how lower respiratory tract infections (LRTIs) before chronic obstructive pulmonary disease (COPD) are associated with future exacerbations and mortality. We ...
Thorax

Predictive capacity of paediatric nasal epithelial cells in sequential CFTR modulator therapy

Background CFTR modulators have transformed cystic fibrosis (CF) treatment, but individual responses vary even among patients with identical CFTR genotypes. This underscores the need for predictive ...
thorax.bmj

Shape-sensing robotic-assisted bronchoscopy with integrated mobile cone-beam CT for small nodules: results from the prospective multicentre CONFIRM study

Background The use of 3D imaging with navigation bronchoscopy has increased with the introduction of mobile cone-beam CT (mCBCT). Shape-sensing robotic-assisted bronchoscopy (ssRAB) integrated with ...
thorax.bmj

Clinical, radiological and pathological features of ABCA3 mutations in children

Pediatric Pulmonary Section, Department of Pediatrics, Baylor College of Medicine, Texas Children’s Hospital, Houston, Texas, USA Background: Mutations in the ABCA3 gene can result in fatal surfactant ...